Myeloablative therapy and cis-retinoic acid confer better survival to high-risk neuroblastoma patients
18 Março 2009
The results of study CCG-3891 were published in March 2009 on Journal of Clinical Oncology. The multicentric study has shown that high-dose myeloablative chemotherapy followed by stem-cell rescue is better than conventional chemotherapy for high-risk neuroblastoma patients. Moreover, addition of cis-retinoic acid treatment after chemotherapy could boost survival in both groups. Standard therapy for high-risk neuroblastoma patients should be therefore myeloablative chemotherapy with autologous stem cell rescue followed by cis-retinoic acid treatment.Read the article here.