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Combined immunotherapy is successful in carcinoma caused by papillomavirus 16
09/27/2018
Researchers at the MD Anderson Cancer Center have published the results of a Phase II trial in the Journal of the American Medical Association (JAMA) Oncology, showing that combined treatment with nivolumabe and ISA101 (a papillomavirus 16 vaccine) has effect in patients with advanced disease.
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Figshare received (and deleted) postprints of 'predatory' journals about a 'mystical effect' (updated)
01/02/2016
Recently, I've posted about the self-archiving of academic conference posters in Figshare. I've pointed out many advantages of Figshare comparing to similar services that allow the archiving of preprints, conference posters, datasets and other types of academic production. I myself have published posters and postprints in Figshare, and maintain my opinion about this service's versatility and utility. For me, it is still superior in many aspects to other alternative academic publishing venues. However... Well, there seems always to be some catch! Look to what I saw today when I opened Figshare's site: -
The problem with p values: how significant are they, really? via Geoff Cumming
11/19/2013
The problem with p values: how significant are they, really?
By Geoff Cumming, La Trobe University
For researchers there’s a lot that turns on the p value, the number used to determine whether a result is statistically significant. The current consensus is that if p is less than .05, a study has reached the holy grail of being statistically significant, and therefore likely to be published. Over .05 and it’s usually back to the drawing board.
But today, Texas A&M University professor Valen Johnson, writing in the prestigious journal Proceedings of the National Academy of Sciences, argues that p less than .05 is far too weak a standard.
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The 3-Year Medical School — Change or Shortchange? — NEJM
09/19/2013
Excerpts from a text published in this week's edition of NEJM:
"Shortening medical school to 3 years, some observers argue, would increase the supply of physicians — perhaps particularly primary care physicians — and reduce the cost of medical training, without compromising clinical care. Data from many years of experiments in shortening medical education, however, suggest that doing so is unwise — a conclusion supported by assessments of the readiness of today's medical school graduates to assume increased clinical responsibility as they enter residency programs. There may be exceptional students capable of accelerated learning and small programs that create unusual opportunities for such students, but we believe that for the typical student seeking an M.D. degree, the duration of medical school should not be shortened." -
International Childhood Cancer Day
02/14/2013
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A Successful and Sustainable Health System — How to Get There from Here — via NEJM
03/19/2012
This is only a fragment of a very interesting essay on the current pitfalls of US health system, but one can see lessons to Brazil, as well. The entire text is worth a read.
In his famous essay on Tolstoy entitled “The Hedgehog and the Fox,” Isaiah Berlin compared a number of historical figures to one or the other animal. Foxes know many things, whereas the hedgehog knows one big thing. Tolstoy, concluded Berlin, was a fox masquerading as a hedgehog: although he believed that history demanded a unifying theme, he could not resist his tendency to see many threads rather than one big cord.
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Prognostic Relevance of Integrated Genetic Profiling in Acute Myeloid Leukemia — via NEJM
03/19/2012
Prognostic Relevance of Integrated Genetic Profiling in Acute Myeloid Leukemia
March 14, 2012 (10.1056/NEJMoa1112304) -
Scientists go Social - via ScienceInsider
03/17/2012
Three Finnish researchers have created an online service that could eventually replace or supplement the current way journals get scientists to peer review submitted manuscripts. Already partnered with the ecology journal Ecography, published by Wiley, Peerage of Science is an innovative social network of scientists to which researchers submit their manuscripts; other members with relevant expertise, alerted by keywords in the papers, will then provide reviews that scientific journals can use to decide whether to publish the work. University of Jyväskylä and the University of Eastern Finland, where the three creators of the service are based, have sponsored the company founded to further build up the service this year.
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Massage's Mystery Mechanism Unmasked - via ScienceNOW
03/17/2012
Massage's healing touch may have more to do with DNA than with good hands. A new study has revealed for the first time how kneading eases sore muscles—by turning off genes associated with inflammation and turning on genes that help muscles heal. The discovery contradicts popular claims that massage squeezes lactic acid or waste products out of tired muscles and could bring new medical credibility to the practice.
For Its New Science Minister Brazil Picks ... A Scientist - via ScienceInsider
02/02/2012
SÃO PAULO, BRAZIL—Brazil has announced that Marco Antônio Raupp, currently president of the Brazilian Space Agency, will become the new minister of science, technology and innovation on 24 January. Unlike the man he will replace, Aloizio Mercadante, a leading figure in the Worker's Party with little background in science, Raupp, 73, has more than 40 years of experience in the field. His appointment has pleased the scientific community, which never warmed to his predecessor.
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